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In patients who have new or worsening respiratory symptoms and are suspected to have developed pneumonitis, interrupt IBRANCE immediately and evaluate the patient. Avoid concomitant use of strong CYP3A inhibitors. View source version on businesswire.

Grapefruit or grapefruit juice may increase their exposure. New York, NY: Humana Press; 2010:3-22. Based on the mechanism of action, IBRANCE can cause fetal harm.

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